Thymic carcinoma in children

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Yaris N., Nas Y., Cobanoglu U., Yavuz M. N.

PEDIATRIC BLOOD & CANCER, vol.47, no.2, pp.224-227, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 2
  • Publication Date: 2006
  • Doi Number: 10.1002/pbc.20468
  • Journal Name: PEDIATRIC BLOOD & CANCER
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.224-227
  • Keywords: childhood, pediatric oncology, rare tumors, thymic carcinoma, HYPERTROPHIC PULMONARY OSTEOARTHROPATHY, EPITHELIAL NEOPLASMS, THYMOMA, TUMORS, CHEMOTHERAPY, THERAPY, BOY
  • Karadeniz Technical University Affiliated: Yes

Abstract

Thymic epithelial neoplasms consist of thymomas, thymic carcinoids, and thymic carcinomas. Carcinomas are malignant tumors of the thymus characterized by obvious cytological anaplasia. They constitute only 4%-14% of thymic epithelial neoplams. Thymic carcinoma rarely occurs in children. Research in the English literature carried out for the present study revealed only 14 cases younger than 18 years-of-age. Here we have reported a 16-year old girl who presented with respiratory distress due to huge anterior mediastinal mass. Histological and immunohistochemical studies confirmed lymphoepithelioma-like thymic carcinoma. She received systemic chemotherapy and radiotherapy. However, she died within 15 months due to progressive disease.