Amniotic fluid lamellar body count as a novel biochemical marker for timing elective caesarean delivery

Kart C., Guven S., Guven E. S. G., Armangil D., Mentese A.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY, vol.35, no.5, pp.451-454, 2015 (SCI-Expanded) identifier identifier identifier


The aim of this study is to evaluate the performance of amniotic fluid lamellar body count (LBC) on the timing of elective caesarean delivery (CS) at >= 39 weeks. After allocating the study group (group I, transient tachypnoea of newborn (TTN), n = 14), an age-matched control group (group II, no TTN, n = 79) was selected for amniotic fluid LBC analysis. The median amniotic fluid LBC levels in group I were significantly lower than in the control group. Furthermore, the median values of mean lamellar body volume, median lamellar body distribution width and lamellar bodycrit in group I were also significantly lower than in group II. The best amniotic fluid LBC value to predict TTN was 40.15 x 10(3)/mu l, with 82.3% sensitivity and 64.3% specificity. The favourable sensitivity and specificity values to predict the TTN for amniotic fluid LBC may suggest using it as an elective caesarean delivery-time scheduling marker.