Carbonic anhydrase I and II autoantibodies in Behcet's disease
ACTA REUMATOLOGICA PORTUGUESA, cilt.42, sa.1, ss.26-31, 2017 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 42 Sayı: 1
- Basım Tarihi: 2017
- Dergi Adı: ACTA REUMATOLOGICA PORTUGUESA
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.26-31
- Anahtar Kelimeler: Autoantibody, Behcet's disease, Carbonic anhydrase, OXIDATIVE STRESS, ANTIBODIES, AUTOIMMUNITY
- Karadeniz Teknik Üniversitesi Adresli: Evet
Özet
Background: Behcet's disease ( BD) is a vasculitis, seen more frequently around the Mediterranean and the Far East, and evinces with oral and genital ulcerations, skin lesions and uveitis. Carbonic anhydrase ( CA) is a metalloenzyme which is widely distributed in the living world, and it is essential for the regulation of acid-base balance. Anti-CA antibodies have been reported in many disorders, such as systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, endometriosis, idiopathic chronic pancreatitis, type 1 diabetes and Graves' disease. The goal of this study was to investigate CA I and II autoantibodies in BD.