Carbonic anhydrase I and II autoantibodies in Behcet's disease


Mentese A., Alver A., Demir S., Sumer A., Yaman S O., Karkucak M., ...Daha Fazla

ACTA REUMATOLOGICA PORTUGUESA, cilt.42, ss.26-31, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 42 Konu: 1
  • Basım Tarihi: 2017
  • Dergi Adı: ACTA REUMATOLOGICA PORTUGUESA
  • Sayfa Sayıları: ss.26-31

Özet

Background: Behcet's disease ( BD) is a vasculitis, seen more frequently around the Mediterranean and the Far East, and evinces with oral and genital ulcerations, skin lesions and uveitis. Carbonic anhydrase ( CA) is a metalloenzyme which is widely distributed in the living world, and it is essential for the regulation of acid-base balance. Anti-CA antibodies have been reported in many disorders, such as systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, endometriosis, idiopathic chronic pancreatitis, type 1 diabetes and Graves' disease. The goal of this study was to investigate CA I and II autoantibodies in BD.