Investigation of bla(KPC) Gene by PCR in Carbapenem-Resistant Escherichia coli and Klebsiella pneumoniae Clinical Isolates in a Tertiary Care Hospital in Turkey

Ozyazici G., ÖZKAYA E., Kaya H., KOCATÜRK SEL S., Altinbasak H., Basari F., ...Daha Fazla

MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS, cilt.8, 2019 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4274/mjima.galenos.2019.2019.3
  • Dergi Adı: MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Anahtar Kelimeler: Carbapenemase, bla(KPC) gene, molecular epidemiology, urinary tract infection, modified Hodge test, SPECTRUM BETA-LACTAMASE, STRAINS, OUTBREAK, ENTEROBACTERIACEAE, IDENTIFICATION, INFECTIONS, ERTAPENEM, SPREAD, UNIT
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Introduction: One of the most common mechanisms in the development of carbapenem resistance is acquiring carbapenemases. A new and different carbapenemase, Klebsiella pneumoniae carbapenemase (KPC), has recently emerged in Turkey. Klebsiella pneumoniae carbapenemases are encoded by the bla(KPC) gene and can be transferred between different species. Reports showing the presence of bla(KPC) gene in isolates from Turkey are limited. The current study aimed to investigate the presence of bla(KPC) gene in carbapenem resistant K. pneumoniae and Escherichia coli isolates in a tertiary care hospital in Turkey.