Simultaneous determination of theophylline and caffeine on novel [Tetra-(5-chloroquinolin-8-yloxy) phthalocyanato] manganese(III)-Carbon nanotubes composite electrode

Kocak C. C., Nas A., Kantekin H., Dursun Z.

TALANTA, cilt.184, ss.452-460, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 184
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.talanta.2018.03.029
  • Dergi Adı: TALANTA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.452-460
  • Anahtar Kelimeler: Manganese phthalocyanine, Carbon nanotubes, Theophylline, Caffeine, Composite electrodes, GLASSY-CARBON ELECTRODE, FILM-MODIFIED ELECTRODE, ELECTROCHEMICAL DETERMINATION, ZINC PHTHALOCYANINE, ASCORBIC-ACID, TETRASULFONATED PHTHALOCYANINE, VOLTAMMETRIC DETERMINATION, III PHTHALOCYANINE, L-CYSTEINE, NANOPARTICLES
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

This work reports the synthesis of new symmetrically substituted manganese(III) phthalocyanine (2eOHMnPc) (2) containing tetra 5-chloroquinolin-8-yloxy group at the peripheral position for the first time. Manganese(III) phthalocyanine (2) was synthesized by cyclotetramerization of 4-(5-chloroquinolin-8-yloxy)phthalonitrile (1) in the presence of corresponding metal salt (manganese(II) chloride). This peripherally substituted phthalocyanine complex (2) was purified by column chromatography and characterized by several techniques such as IR, mass and UV-Visible spectral data. This novel synthesized phthalocyanine was mixed with multiwalled carbon nanotubes in order to prepare the novel catalytic surface on glassy carbon electrode for theophylline and caffeine detection in acidic medium. The novel composite electrode surfaces were characterized by scanning electron microscopy and electrochemical impedance spectroscopy. Individual and simultaneous determination of theophylline and caffeine were studied by differential pulse voltammetry. The detection limits were individually calculated for theophylline and caffeine as 6.6 x 10(-9) M and 5.0 x 10(-8) M, respectively. In simultaneous determination, LODs were calculated for theophylline and caffeine as 8.1 x 10(-9) M and 3.0 x 10(-7) M, respectively. The practical applicability of the proposed modified electrode was tested for the determination of theophylline and caffeine in green tea, cola and theophylline serum.