Radiotherapy in the management of classic Kaposi's sarcoma: A single institution experience from Northeast Turkey

Creative Commons License

Kandaz M., Bahat Z., Guler O. C., Canyılmaz E., Melikoğlu M., Yoney A.

DERMATOLOGIC THERAPY, vol.31, no.4, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.1111/dth.12605
  • Journal Name: DERMATOLOGIC THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: classic Kaposi sarcoma, radiotherapy, RADIATION-THERAPY, EPIDEMIOLOGY, AFRICAN, ISRAEL
  • Karadeniz Technical University Affiliated: Yes

Abstract

Kaposi sarcoma is a rare adult neoplasm and there has been no certain consensus on standard treatment, either local or systemic. Radiotherapy is an effective, suitable treatment modality. Between 1996 and 2016, patients who were diagnosed with Kaposi sarcoma and referred to our clinic for radiotherapy were included in this retrospective study. Ninety-two patients were examined in total and it was diagnosed that all the patients had non-HIV associated Kaposi's sarcoma. There were 36 (39%) females and 56 (61%) males arid female to male ratio was 2/3. Median age at presentation was 72 (30-93) years. Sixty-eight patients (77%) were treated with 8 Gy (1 fraction), 15 patients (16%) were treated with 20 Gy (2 Gy/fraction), four patients (4%) were treated 25 Gy (2.5 Cy/fraction), and five patients (6%) were treated 30 Gy (3 Gy/fraction). The median follow-up time was 72 (5-192) months. The complete response at 5 years was 91.6% with >20 Gy arid 89.6% with 8 Gy. Radiotherapy is an effective, suitable treatment modality of Classic Kaposi sarcoma and usually, radiotherapy is well tolerated with minimal side effects.