Lipoprotein phospholipase A2 in patients with isolated coronary artery ectasia

KORKMAZ L., ERKUŞ E., KIRIŞ A., AĞAÇ M. T., ACAR Z., TURAN T., ...More

CLINICAL RESEARCH IN CARDIOLOGY, vol.100, no.6, pp.511-514, 2011 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 100 Issue: 6
  • Publication Date: 2011
  • Doi Number: 10.1007/s00392-010-0274-z
  • Journal Name: CLINICAL RESEARCH IN CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.511-514
  • Karadeniz Technical University Affiliated: Yes

Abstract

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is among the multiple cardiovascular biomarkers that have been associated with increased cardiovascular disease. Lp-PLA2 appears, however, to be relatively unique in its high specificity for vascular inflammation as opposed to systemic inflammation, its low biologic variability, and its direct role in the causal pathway of plaque inflammation. Nevertheless, the relation between LP-PLA2 and isolated coronary artery ectasia (CAE) has not been investigated yet. The aim of our study was to assess this relation.