In this study, exergy is considered as the confluence of energy, environment, and sustainable development. The basis for this treatment is the interdisciplinary character of exergy and its relation to each of these disciplines. The primary objective of this study is to present a unified exergy-based structure that provides useful insights and direction to those involved in exergy, environment, and sustainable development for analyzing and addressing appropriately each of these areas using exergy concepts. The thermodynamic concept of chemical exergy is introduced for water quality evaluation. In this study, physical and chemical analyses were performed of the water samples taken from the determined three stations in the Galyan River that will feed the Atasu Dam, which is under construction in order to supply the drinking and using water necessary for Trabzon province.