SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, vol.58, pp.90-95, 2018 (Journal Indexed in SCI)
Article / Article
Title of Journal :
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Valproic acid, Topiramate, Antiepileptic drugs, Endocrine side-effect, Insulin, Glucose, Leptin, NPY, Ghrelin, WEIGHT-GAIN, ACID, THERAPY, GIRLS, CARBAMAZEPINE, RESISTANCE
Purpose: Although some drugs used in the treatment of epilepsy are known to affect body weight, the hormonal factors responsible have not been sufficiently described. The purpose of this study was to compare insulin, leptin, neuropeptide Y and ghrelin levels in children with epilepsy receiving monotherapy with topiramate (TPM) and valproic acid (VPA), the drugs whose effects on body weight have been most discussed, with those of a control group.