A retrospective comparison of concurrent 5-fluoro-uracil or oral UFT in postoperative chemoradiation for gastric adenocarsinoma


Yoney A. , BATI Y., AKBORU H., ISIKLI L., UNSAL M. A.

CANCER RADIOTHERAPIE, vol.14, no.1, pp.19-23, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 1
  • Publication Date: 2010
  • Doi Number: 10.1016/j.canrad.2009.09.004
  • Title of Journal : CANCER RADIOTHERAPIE
  • Page Numbers: pp.19-23

Abstract

Purpose. - 5-fluoro-uracil (FU) is a common agent in postoperative chemoradiation in gastric adenocarcinoma. However, FU is not well tolerated in a significant proportion of patients. UFT, a fixed combination of the oral FU prodrug tegafur with uracil, is one of the agents used instead of FU in such cases. We retrospectively compared the toxicity, local and distant control and Survival rates with FU or oral UFT during concurrent radiotherapy to assess the role of UFT instead of FU.