Copy For Citation
ULUSOY Ş., Özkan G., Mungan S., ÖREM A., YULUĞ E., Alkanat M., ...More
LIFE SCIENCES, vol.103, no.2, pp.101-110, 2014 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
103
Issue:
2
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Publication Date:
2014
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Doi Number:
10.1016/j.lfs.2014.03.030
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Journal Name:
LIFE SCIENCES
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.101-110
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Keywords:
Contrast-induced nephropathy, Caspases, Calpains, Grape seed proanthocyanidin extract, GSPE, N acetyl cysteine, NAC, N-ACETYLCYSTEINE, CASPASE-1-DEFICIENT MICE, INDUCED APOPTOSIS, RENAL-FUNCTION, HYPOXIA, MEDIA, CELLS
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Karadeniz Technical University Affiliated:
Yes
Abstract
Aims: Our study was intended to evaluate the role of inducible nitric oxide synthase (iNOS), endothelial nitric oxide synthase (eNOS), caspases 1 and 3 and calpain 1 in the pathogenesis of contrast-induced nephropathy (CIN) and to compare the protective effects of N acetyl cysteine (NAC) and grape seed proanthocyanidin extract (GSPE) against the development of CIN.