The effects of heparin on DLD-1 colon cancer cell line

Uzun Y., Akdogan E., Ozdemir F., Ovali E.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.110, sa.1, ss.3-6, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 110 Sayı: 1
  • Basım Tarihi: 2009
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3-6
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background: Patients with cancer are frequently treated with anticoagulants, including heparin, to prevent or to treat the deep vein thrombosis. It has been indicated that heparin affects the survival of patients with cancer. Also, the apoptotic and antiproliferative effects of heparin on some cancers has been demonstrated. Experimental studies support the hypothesis that cancer progression can be influenced by heparin, but the results of these studies are not conclusive.