Late diagnosis of severe colchicine intoxication


GUVEN A. , Bahat E., AKMAN S., ARTAN R., EROL M.

PEDIATRICS, cilt.109, ss.971-973, 2002 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 109 Konu: 5
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1542/peds.109.5.971
  • Dergi Adı: PEDIATRICS
  • Sayfa Sayıları: ss.971-973

Özet

A 4-year-old Turkish girl was referred to our hospital with the findings of encephalopathy and pancytopenia. She had a history of severe abdominal cramps and gastrointestinal bleeding. A confused state, muscle pain and weakness, erythema-bullous and erythema-nodosum-like skin lesions, and alopecia were observed at her hospitalization. All of these symptoms resolved on follow-up. On laboratory investigation severe thrombocytopenia and leukopenia, mild anemia, a moderate increase in aspartate aminotransferase and alanine aminotransferase levels were detected. After reevaluating her medical history, it was learned that she had accidentally taken 1.3 to 1.5 mg/kg of colchicine 3 to 4 days before her first hospitalization.