Phytochemical studies on the seeds, pseudofruits, and roots of Rosa pimpinellifolia

GÜVEN L., ÖZGEN U., SEÇEN H., ŞENER S. Ö., BADEM M., Celik G., ...Daha Fazla

JOURNAL OF RESEARCH IN PHARMACY, cilt.25, sa.2, ss.153-163, 2021 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.29228/jrp.6
  • Dergi Adı: JOURNAL OF RESEARCH IN PHARMACY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.153-163
  • Anahtar Kelimeler: Rosa pimpinellifolia, Triterpenoid glycosides, phenolic compounds, fatty acid, FATTY-ACID-COMPOSITION, MEDICINAL-PLANTS, ANTIMICROBIAL ACTIVITIES, TRITERPENOID SAPONINS, ESSENTIAL OILS, ANTIOXIDANT, CONSTITUENTS, FLOWERS, FRUITS, RUGOSA
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

The roots and pseudofruits of Rosa pimpinellifolia (Rosaceae) are used in traditional medicine as hemorrhoids, various infections, abdominal pain complaints, heart disease, flu, cold, and anemia treatment in Turkey. In this study, the phytochemical composition of the R. pimpinellifolia was revealed by using chromatographic and spectroscopic techniques. Two condensed tannin precursor, (-)-catechin (1), the mixture of catechin and epicatechin (2) and three triterpenoid glycosides, kaji-ichigoside F1 (3), 2a,3 beta,19a trihydroxyurs-12-en-28-O-beta-D-glucopyranoside (4), 2a,3 beta,19a,23 beta-tetrahydroxyurs-12-en-28-O-beta-D-glucopyranoside (5) were isolated from the roots of R. pimpinellifolia. The isolation studies were performed by column chromatography. The chemical structures of the isolated compounds were elucidated with 1H and 13C NMR spectroscopy. Total phenolic compound contents were determined as 31.1937 mg/g dry extract in the pseudofruit; 9.8909 mg/g dry extract in the root via HPLC. The seeds of R. pimpinellifolia were extracted with diethyl ether in Soxhlet apparatus. The methyl esters of fatty acid were obtained from fixed oil and analyzed by GC/MS. The total ratio of unsaturated fatty acids in the seeds was 93.4%; containing 51.40% ratio of linoleic acid and 41.20% ratio of homo-gamma-linolenic acid.