A new player in chronic kidney disease mineral and bone disorder: tenascin-C

OZKAN G., ULUSOY Ş., GÜVERCİN B., MENTEŞE A., KARAHAN S. C., YAVUZ A.

INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, vol.38, no.9, pp.481-487, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 9
  • Publication Date: 2015
  • Doi Number: 10.5301/ijao.5000436
  • Journal Name: INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.481-487
  • Karadeniz Technical University Affiliated: Yes

Abstract

Aims: Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a condition frequently observed in CKD. The search for a reliable and easy to use biomarker in the diagnosis of CKD-MBD is continuing. Tenascin-C (TN-C) is an important extracellular (ECM) protein synthesized by osteoblasts during bone growth and morphogenesis. The purpose of this study was to assess the relation between inflammation and MBD and TN-C in HD patients and to identify a new marker that can be used to help diagnose CKD-MBD.