Synthetic route for racemic synthesis of <i>Trans</i>-(1R,S,3R,S)-2-methylene-1,3-dithiane-1,3-dioxide and reactivity with N-carbethoxy-1,2-dihydropyridine as a dienophile

Gültekin, Z; BAYRAK, HACER; Frey, W

Synthetic route for racemic synthesis of <i>Trans</i>-(1R,S,3R,S)-2-methylene-1,3-dithiane-1,3-dioxide and reactivity with N-carbethoxy-1,2-dihydropyridine as a dienophile

ASIAN JOURNAL OF CHEMISTRY, cilt.18, sa.2, ss.1474-1480, 2006 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 18 Sayı: 2
Basım Tarihi: 2006
Dergi Adı: ASIAN JOURNAL OF CHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1474-1480
Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

Trans-(1R,S, 3R,S)-2-methylene- 1,3-dithiane- 1,3-dioxide has been prepared in 22% yield in three steps and cycloaddition of (4a) with N-carbethoxy-1,2-dihydropyridine gave a moderate diastereoselective (76 : 24) in 20% yield. All the major compounds (4b) and (7a) were determined by X-ray analysis.