The Assessment of Left Ventricular Systolic Asynchrony in Patients with Primary Hyperparathyroidism

Kiris A., Erem C., Kiris G., NUHOĞLU İ., Karaman K., Civan N., ...Daha Fazla

ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES, cilt.28, sa.9, ss.955-960, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 9
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1111/j.1540-8175.2011.01468.x
  • Dergi Adı: ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.955-960
  • Anahtar Kelimeler: hyperparathyroidism, left ventricular asynchrony, tissue synchronization imaging, CARDIAC RESYNCHRONIZATION THERAPY, MILD PRIMARY HYPERPARATHYROIDISM, HEART-FAILURE, SUCCESSFUL PARATHYROIDECTOMY, MYOCARDIAL-INFARCTION, HYPERTENSIVE PATIENTS, DIABETES-MELLITUS, BRACHIAL-ARTERY, ABNORMALITIES, DISEASE
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Objectives: Primary hyperparathyroidism (PHP) is associated with a variety of cardiovascular disturbances such as left ventricular (LV) hypertrophy, diastolic cardiac dysfunction, and hypertension. LV asynchrony is defined as the loss of the simultaneous peak contraction of corresponding cardiac segments. The objective of this study was to assess systolic asynchrony in patients with overt hyperparthyroidism. Methods: Asynchrony was evaluated in 22 patients with PHP and 24 controls. All the patients and controls were subjected to a tissue synchronization imaging (TSI). The time to regional peak systolic tissue velocity (Ts) in LV by the six-basal-six-midsegmental model was measured on ejection phase TSI images and four TSI parameters of systolic asynchrony were computed. Results: All TSI parameters of LV asynchrony increased in patients with PHP patients compared to the controls: the standard deviation (SD) of the 12 LV segments Ts (37.3 +/- 20.6 vs. 21.5 +/- 11.1, P = 0.01); the maximal difference in Ts between any 2 of the 12 LV segments (111.2 +/- 59.8 vs. 70.2 +/- 32.1, P = 0.01); the SD of the 6 basal LV segments (42.9 +/- 36.4 vs. 18.5 +/- 13, P = 0.003); and the maximal difference in Ts between any 2 of the 6 basal LV segments (89.6 +/- 50.5 vs. 48 +/- 31.1, P = 0.003). Conclusion: Patients with PHP show an evidence of LV asynchrony by TSI. Asynchrony may contribute to the harmful cardiovascular effects of PHP. (Echocardiography 2011;28:955-960)