Is resveratrol a potential substitute for leuprolide acetate in experimental endometriosis?

TEKIN Y. B., GÜVEN S., KIRBAS A., KALKAN Y., TUMKAYA L., Guven E. S. G.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, cilt.184, ss.1-6, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 184
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.ejogrb.2014.10.041
  • Dergi Adı: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1-6
  • Anahtar Kelimeler: Endometriosis, Rat model, Resveratrol, Leuprolide acetate, Treatment, RAT MODEL, REGRESSION, TISSUE, INVASIVENESS, ANGIOGENESIS, INFLAMMATION, INHIBITOR, EXPLANTS, IMMUNE
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Objective: Resveratrol, a phytoalexin polyphenol, has anti-angiogenic, antioxidant, anti-inflammatory properties. We aimed to compare the anti-inflammatory and anti-angiogenic effects of resveratrol and leuprolide acetate (LA) in an experimental endometriosis model.