Protective effect of curcumin against contrast induced nephropathy in rat kidney: what is happening to oxidative stress, inflammation, autophagy and apoptosis?

BÜYÜKLÜ M., KANDEMİR F. M., ÖZKARACA M., Set T., BAKIRCI E. M., Topal E.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.18, no.4, pp.461-470, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 4
  • Publication Date: 2014
  • Journal Name: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.461-470
  • Keywords: Angiography, Nephropathy, Curcumin, Contrast, Autophagy, Apoptosis, NITRIC-OXIDE SYNTHASE, N-ACETYLCYSTEINE, DIABETIC-NEPHROPATHY, RENAL-INSUFFICIENCY, SODIUM-BICARBONATE, INDUCED TOXICITY, CELL APOPTOSIS, PREVENTION, MEDIA, ANTIOXIDANT
  • Karadeniz Technical University Affiliated: Yes

Abstract

BACKGROUND: Currently, the number of imaging and interventional procedures that use contrast agents (CAs) is gradually increasing. Oxidative stress plays a significant role in its pathophysiology. Curcumin (CC) is a natural substance with strong antioxidant efficacy.