Protective effect of curcumin against contrast induced nephropathy in rat kidney: what is happening to oxidative stress, inflammation, autophagy and apoptosis?


BÜYÜKLÜ M., KANDEMİR F. M. , ÖZKARACA M., Set T., BAKIRCI E. M. , Topal E.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.18, no.4, pp.461-470, 2014 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 4
  • Publication Date: 2014
  • Journal Name: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.461-470
  • Keywords: Angiography, Nephropathy, Curcumin, Contrast, Autophagy, Apoptosis, NITRIC-OXIDE SYNTHASE, N-ACETYLCYSTEINE, DIABETIC-NEPHROPATHY, RENAL-INSUFFICIENCY, SODIUM-BICARBONATE, INDUCED TOXICITY, CELL APOPTOSIS, PREVENTION, MEDIA, ANTIOXIDANT

Abstract

BACKGROUND: Currently, the number of imaging and interventional procedures that use contrast agents (CAs) is gradually increasing. Oxidative stress plays a significant role in its pathophysiology. Curcumin (CC) is a natural substance with strong antioxidant efficacy.