Akademik Veri Yönetim Sistemi
Proceedings Of The Institution Of Mechanical Engineers Part H-Journal Of Engineering In Medicine, cilt.56, sa.4, ss.120-135, 2022 (SCI-Expanded)
Scaffolds provide a suitable
environment for the bone tissue to maintain its self-healing ability and help
new bone-cell formation by creating structures with similar mechanical
properties to the surrounding tissue. In the modeling of the scaffolds, an optimum
environment is tried to be provided by changing the geometrical properties of
the cell architecture such as porosity, pore size, and specific surface area. For this purpose, different design approaches have been
used in studies to change these properties. This
study aims to determine whether scaffolds with similar porosities modeled by
different design approaches exhibit distinct biomechanical behaviors or not.
By using the Diamond lattice architecture, two different design approaches were
constituted. The first approach has constant wall thickness and
variable cell size, whereas the second approach contains variable wall
thickness and constant cell size. The usage of different design approaches affected
the amount of specific surface area in models with similar porosity. Mechanical
compression tests were conducted via Finite Element Analysis, while the
permeability performance of configurations with similar porosities (50%, 60%,
70%, 80%, and 90%) was evaluated by using Computational Fluid Dynamics. The
mechanical results revealed that the structural strength decreased with
increasing porosity. Since their higher specific surface area causes lower
pressure drops, the second group exhibits better permeability. In addition, it
was found that to evaluate the wall shear stresses occurring on the scaffold
surfaces properly, it is essential to consider the stress distributions within
the scaffold rather than the maximum values.