Evaluation of the height of the corpus callosum body region in fetal meningomyelocele malformation


AKBAŞ H., Guven E. S. G., GÜVEN S., KIZILIRMAK R., ALBAYRAK M., AYDOĞAN Z., ...Daha Fazla

Journal of Gynecology Obstetrics and Human Reproduction, cilt.52, sa.7, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 52 Sayı: 7
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1016/j.jogoh.2023.102619
  • Dergi Adı: Journal of Gynecology Obstetrics and Human Reproduction
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, MEDLINE
  • Anahtar Kelimeler: Arnold-chiari, Corpus callosum, Fetal MRI, Meningomyelocele, Open spina bifida, Prenatal diagnosis, Ventriculomegaly
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Purpose: To investigate height of the corpus callosum (CC) in order to describe the corpus callosum anomalies in fetuses with meningomyelocele (MMC) and compare these findings with the corpus callosum of healthy fetuses. Methods: In this study, fetal MRI examinations were performed on 44 fetal MMC malformation cases. As the control group, 34 fetal MRI examinations, which were anatomically normal, were evaluated retrospectively. In the study group, lateral ventricle diameter, the level and diameter of the MMC defect, and CC height were measured. In the control group, CC height and lateral ventricular diameter were measured. Results: The mean CC body height was 1.36 mm in the study group, and 2.48 mm in the control group. The height of the CC body region of the study population was inclined to be thinner compared with the control population (p<0.001). Conclusions: The fact that the height of the CC body region was found to be thinner in fetal MRI in cases of MMC compared with normal fetuses suggests that various callosal anomalies are uncertain, investigation of additional callosal anomalies may be beneficial in the decision for the continuation of pregnancy, and termination or intrauterine surgery in cases with MMC. Further large case group studies are needed.