Cytotoxic and Apoptotic Effect ofIris taochia Plant Extracts on Human Breast Cancer (MCF-7) Cells

Yazgan B., Ozcelik O., Ayar A., RENDA G., Yildirim T.

CURRENT PROTEOMICS, vol.19, no.1, pp.91-101, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.2174/1570164618666210402152159
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE
  • Page Numbers: pp.91-101
  • Keywords: Iris taochia, breast cancer, cytotoxicity, apoptosis, bcl2 family, MCF-7 cells, HEAT-SHOCK PROTEINS, DRUG-RESISTANCE, IRIS, PROLIFERATION, BAX, ANTIOXIDANT, TRITERPENES, TARGET
  • Karadeniz Technical University Affiliated: Yes


Introduction: Iris taochia is an endemic plant in Turkey. Iris species has many biological effects such as antibacterial, antiinflammatory, antioxidant and anticancer properties. Apoptosis is a programmed cell death and this mechanism regulates the death of cancer cells.