Cytotoxic and Apoptotic Effect ofIris taochia Plant Extracts on Human Breast Cancer (MCF-7) Cells

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Yazgan B., Ozcelik O., Ayar A., RENDA G., Yildirim T.

CURRENT PROTEOMICS, cilt.19, sa.1, ss.91-101, 2022 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 19 Sayı: 1
• Basım Tarihi: 2022
• Doi Numarası: 10.2174/1570164618666210402152159
• Dergi Adı: CURRENT PROTEOMICS
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE
• Sayfa Sayıları: ss.91-101
• Anahtar Kelimeler: Iris taochia, breast cancer, cytotoxicity, apoptosis, bcl2 family, MCF-7 cells, HEAT-SHOCK PROTEINS, DRUG-RESISTANCE, IRIS, PROLIFERATION, BAX, ANTIOXIDANT, TRITERPENES, TARGET
• Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Introduction: Iris taochia is an endemic plant in Turkey. Iris species has many biological effects such as antibacterial, antiinflammatory, antioxidant and anticancer properties. Apoptosis is a programmed cell death and this mechanism regulates the death of cancer cells.