In this study, the use of glass waste as aggregate in asphalt mixtures was investigated. Maximum glass aggregate size options of 0.075, 2.00, 4.75 and 9.5 mm. were selected. Conventional bitumen, nanoclay-modified bitumen and hydrated lime-modified bitumen were used. Dense graded asphalt mixtures were designed according to the Marshall method. Mixtures were evaluated for low-temperature cracking, resistance to water damage, fatigue, and permanent deformation behavior with repeated creep, indirect tensile strength, indirect tensile fatigue, modified Lottman and Hamburg wheel tracking tests. Increasing glass aggregate size reduced the water damage resistance of asphalt mixtures because of the smooth surface of the glass particles and nanoclay and hydrated lime modification improved the mechanical properties of the asphalt mixtures. Using 2.00 mm sized maximum glass aggregate showed relatively less water damage and deformation properties due to higher internal friction which is due to the greater angularity of the glass particles. In addition, there was a significant correlation between repeated creep test, modified Lottman methods and Hamburg Wheel tracking test from the viewpoint of deformation and water damage assessments.