Circulating platelet-leukocyte aggregates in patients with inflammatory bowel disease


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Tekelioğlu Y., Uzun H., Güçer H.

JOURNAL OF THE CHINESE MEDICAL ASSOCIATION, cilt.76, sa.4, ss.182-185, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 76 Sayı: 4
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.jcma.2012.12.015
  • Dergi Adı: JOURNAL OF THE CHINESE MEDICAL ASSOCIATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.182-185
  • Anahtar Kelimeler: disease activity, inflammatory bowel disease, platelet-leukocyte aggregate, SURFACE P-SELECTIN, CROHNS-DISEASE, ADHESION
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background: Inflammatory bowel diseases (IBDs), Crohn's disease, and ulcerative colitis are considered to be chronic inflammatory disorders implicated with recurrent tissue damage to the intestine. There is a positive correlation between platelet-leukocyte aggregates and ischemic vascular risk. There are limited data about the relationship between platelet leukocyte aggregates and IBD. This study was designed to determine whether platelet-leukocyte aggregates increase in IBD, and whether a relationship exists between the elevation of platelet-leukocyte aggregates and disease activity.