Circulating platelet-leukocyte aggregates in patients with inflammatory bowel disease

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Tekelioğlu Y., Uzun H., Güçer H.

JOURNAL OF THE CHINESE MEDICAL ASSOCIATION, vol.76, no.4, pp.182-185, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 76 Issue: 4
  • Publication Date: 2013
  • Doi Number: 10.1016/j.jcma.2012.12.015
  • Journal Name: JOURNAL OF THE CHINESE MEDICAL ASSOCIATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.182-185
  • Keywords: disease activity, inflammatory bowel disease, platelet-leukocyte aggregate, SURFACE P-SELECTIN, CROHNS-DISEASE, ADHESION
  • Karadeniz Technical University Affiliated: Yes

Abstract

Background: Inflammatory bowel diseases (IBDs), Crohn's disease, and ulcerative colitis are considered to be chronic inflammatory disorders implicated with recurrent tissue damage to the intestine. There is a positive correlation between platelet-leukocyte aggregates and ischemic vascular risk. There are limited data about the relationship between platelet leukocyte aggregates and IBD. This study was designed to determine whether platelet-leukocyte aggregates increase in IBD, and whether a relationship exists between the elevation of platelet-leukocyte aggregates and disease activity.