The effect of different anesthesia techniques on cerebral oxygenation in thoracic surgery

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Akdoğan A., Beşir A., Kutanis D., Ertürk E., Tuğcugil E., Saylan S.

CIRUGIA Y CIRUJANOS, vol.90, no.S1, pp.52-60, 2022 (SCI-Expanded)

  • Publication Type: Article / Article
  • Volume: 90 Issue: S1
  • Publication Date: 2022
  • Doi Number: 10.24875/ciru.21000440
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Page Numbers: pp.52-60
  • Karadeniz Technical University Affiliated: Yes


Objective: One-lung ventilation may cause negative changes in the oxygenation of cerebral tissue which results in post-operative cognitive dysfunction. We compared the potential effects of total intravenous anesthesia and inhalation general anesthesia techniques on cerebral tissue oxygenation Materials and methods: In this prospective double-blind trial, patients whose

standard anesthesia induction was done were randomly divided into two groups as group total intravenous anesthesia using

propofol (Group T, n = 30) and group inhalation general anesthesia using sevoflurane (Group I, n = 30) based on anesthesia

maintenance. The intraoperative cerebral oxygen saturation and pre-post-operative mini-mental status test scores of the patients

were monitored and recorded. Results: Baseline characteristics were similar between the two groups. The decrease of cerebral oxygen saturation more than 20% in total intravenous anesthesia group was significantly higher than inhalation group

(p < 0.05). In both groups, the mini-mental status test values at the post-operative 3rd h were significantly lower than the preoperative and post-operative 24th h values (p < 0.05). Conclusions: Inhalation general anesthesia provided better cerebral

tissue oxygenation in thoracic surgery with one-lung ventilation compared to total intravenous anesthesia. However, there was

no significant correlation between the presence of desaturation and post-operative cognitive dysfunction