CIRUGIA Y CIRUJANOS, cilt.90, sa.S1, ss.52-60, 2022 (SCI-Expanded)
Objective: One-lung ventilation may cause negative changes in the oxygenation of cerebral tissue which results in post-operative cognitive dysfunction. We compared the potential effects of total intravenous anesthesia and inhalation general anesthesia techniques on cerebral tissue oxygenation Materials and methods: In this prospective double-blind trial, patients whose
standard anesthesia induction was done were randomly divided into two groups as group total intravenous anesthesia using
propofol (Group T, n = 30) and group inhalation general anesthesia using sevoflurane (Group I, n = 30) based on anesthesia
maintenance. The intraoperative cerebral oxygen saturation and pre-post-operative mini-mental status test scores of the patients
were monitored and recorded. Results: Baseline characteristics were similar between the two groups. The decrease of cerebral oxygen saturation more than 20% in total intravenous anesthesia group was significantly higher than inhalation group
(p < 0.05). In both groups, the mini-mental status test values at the post-operative 3rd h were significantly lower than the preoperative and post-operative 24th h values (p < 0.05). Conclusions: Inhalation general anesthesia provided better cerebral
tissue oxygenation in thoracic surgery with one-lung ventilation compared to total intravenous anesthesia. However, there was
no significant correlation between the presence of desaturation and post-operative cognitive dysfunction