The aim of this paper is to investigate how the soil-structure interaction affects sloshing response of the elevated tanks with frame staging system on different soil conditions. For this purpose, the elevated tanks with frame staging system which are built on six different soil profiles are analyzed for both embedded and surface foundation cases. Thus, considering these six different profiles described in well-known earthquake codes as supporting medium, a series of transient analysis have been performed to assess the effect of both fluid sloshing and soil-structure interaction. Fluid-Elevated Tank-Soil/Foundation systems are modeled with the finite element (FE) technique. In these models fluid-structure interaction is taken into account by implementing Lagrangian fluid FE approximation into the general purpose structural analysis computer code ANSYS. A 3-D FE model with viscous boundary is used in the analyses of elevated tanks-soil/foundation interaction. Formed models are analyzed for embedment and no embedment cases. Finally results from analyses showed that the soil-structure interaction for the elevated tanks affected the sloshing response of the fluid inside the vessel.