Application of quantum dot-based biosensor to the conjunctiva in Wistar albino rats


NUR İ. H., SAÇMACI Ş., Keles H., Abumandour M., TESTERECİ H.

ANATOMIA HISTOLOGIA EMBRYOLOGIA, vol.49, no.2, pp.167-172, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.1111/ahe.12508
  • Journal Name: ANATOMIA HISTOLOGIA EMBRYOLOGIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.167-172
  • Karadeniz Technical University Affiliated: Yes

Abstract

This study was conducted to get an idea about the distribution of the lymphatic fluid in conjunctiva throughout the body parts. For this purpose, Qdot655 (QD), fluorescence nanoparticles, spread onto the conjunctiva were used on Wistar albino rats. Drainage of QD particles from conjunctiva was followed up via fluorescence images at different hours on body parts such as eye, ears, forearms, hind legs and tails. The first fluorescence signals within the 30th minutes following administration of QD were observed in the nasal region and the anterior extremities. Whereas within 60th minutes following QD spread, fluorescent signals were obtained from the ears, forearms, hind legs and tail of the female and male rats.