Antioxidant capacity, anti-acetylcholinesterase activity and inhibitory effect on lipid peroxidation in mice brain homogenate of Achillea millefolium

BARUT E. N., Barut B., ENGİN S., YILDIRIM S., YAŞAR A., Turkis S., ...More

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.42, no.4, pp.493-502, 2017 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.1515/tjb-2017-0084
  • Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.493-502
  • Keywords: Acetylcholinesterase, Alzheimer's disease, Brain, Lipid peroxidation, Sodium nitroprusside, PERFORMANCE LIQUID-CHROMATOGRAPHY, IN-VITRO ANTIOXIDANT, ALZHEIMERS-DISEASE, RAT-BRAIN, ANTIMICROBIAL ACTIVITY, EXTRACTS, L., ACETYLCHOLINESTERASE, ASSAY, WILD
  • Karadeniz Technical University Affiliated: Yes

Abstract

Objective: Achillea millefolium (A. millefolium) is a traditional herbal medicine that contains natural compounds with antioxidant activities and is used for a wide range of conditions among people. The aim of our study was to investigate antioxidant and anti-acetylcholinesterase activities of A. millefolium extracts to determine its potential therapeutic usage in Alzheimer's disease (AD).