Successful use of fondaparinux in a patient with heparin-induced thrombocytopenia while on extracorporeal membrane oxygenation after mitral valve redo surgery

Parlar A. I., Sayar U., Cevirme D., Yuruk M. A., Mataraci I.

INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, cilt.37, sa.4, ss.344-347, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5301/ijao.5000302
  • Dergi Adı: INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.344-347
  • Anahtar Kelimeler: Extracorporeal membrane oxygenation, Fondaparinux, Heparin-induced thrombocytopenia
  • Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

In patients with respiratory failure and impairment of the left ventricle, arteriovenous extracorporeal membrane oxygenation (ECMO) offers further therapeutic options. Systemic anticoagulation is mandatory and heparin is routinely administrated. However, repeated exposure to heparin may cause heparin-induced thrombocytopenia (HIT) and carries a risk of thrombotic mortality and morbidity. We present a patient who developed HIT during ECMO support and was treated successfully and safely by fondaparinux. Fondaparinux can be used for thromboembolic treatment or prophylaxis in a patient with HIT.