Interobserver Variability in Mitotic Count for Meningioma Grading: How Can We Reduce It?

Saygin İ., Cakir E., Ercin M. E.

TURKISH NEUROSURGERY, vol.30, no.5, pp.643-650, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 5
  • Publication Date: 2020
  • Doi Number: 10.5137/1019-5149.jtn.26252-19.2
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.643-650
  • Keywords: Brain neoplasm, Grade concordance, Interobserver variability, Meningioma, Mitosis, CENTRAL-NERVOUS-SYSTEM, PROGNOSTIC-SIGNIFICANCE, PHOSPHOHISTONE H3, RECURRENCE, SURGERY, TUMORS
  • Karadeniz Technical University Affiliated: Yes


AIM: To evaluate the interobserver variability in determining the number of mitoses in 10 high-power field (HPF) and thus the tumor grade, and to investigate how to reduce grade discordance between the observers and the most useful method to identify the patients who would receive an additional treatment.