The effect of ethyl pyruvate and N-acetylcysteine on ischemia-reperfusion injury in an experimental model of ischemic stroke

Turkmen, SÜHA; Gonenc, Ozgen; Karaca, YUNUS; Menteşe, AHMET; Demir, SELİM; Beyhun, NAZIM; Şahin, AYNUR; Gündüz, ABDÜLKADİR; Yuluğ, ESİN; Türedi, SÜLEYMAN

doi:10.1016/j.ajem.2016.06.003

The effect of ethyl pyruvate and N-acetylcysteine on ischemia-reperfusion injury in an experimental model of ischemic stroke

Turkmen S., Gonenc O. C., Karaca Y., Menteşe A., Demir S., Beyhun E., ...More

AMERICAN JOURNAL OF EMERGENCY MEDICINE, vol.34, no.9, pp.1804-1807, 2016 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 34 Issue: 9
Publication Date: 2016
Doi Number: 10.1016/j.ajem.2016.06.003
Journal Name: AMERICAN JOURNAL OF EMERGENCY MEDICINE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1804-1807
Karadeniz Technical University Affiliated: Yes

Abstract

Introduction: Reperfusion therapies play an important role in early-period treatment for patients presenting to the emergency department due to stroke. However, the ischemia-reperfusion injury that may occur with reperfusion must then be considered. The purpose of this study was to determine the effectiveness of N-acetylcysteine (NAC) and ethyl pyruvate in preventing ischemia-reperfusion injury.