The effect of ethyl pyruvate and N-acetylcysteine on ischemia-reperfusion injury in an experimental model of ischemic stroke


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Turkmen S. , Gonenc O. C. , Karaca Y. , Menteşe A. , Demir S. , Beyhun E. , ...More

AMERICAN JOURNAL OF EMERGENCY MEDICINE, vol.34, no.9, pp.1804-1807, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 9
  • Publication Date: 2016
  • Doi Number: 10.1016/j.ajem.2016.06.003
  • Title of Journal : AMERICAN JOURNAL OF EMERGENCY MEDICINE
  • Page Numbers: pp.1804-1807

Abstract

Introduction: Reperfusion therapies play an important role in early-period treatment for patients presenting to the emergency department due to stroke. However, the ischemia-reperfusion injury that may occur with reperfusion must then be considered. The purpose of this study was to determine the effectiveness of N-acetylcysteine (NAC) and ethyl pyruvate in preventing ischemia-reperfusion injury.