The effect of ethyl pyruvate and N-acetylcysteine on ischemia-reperfusion injury in an experimental model of ischemic stroke

Turkmen, SÜHA; Gonenc, Ozgen; Karaca, YUNUS; Menteşe, AHMET; Demir, SELİM; Beyhun, NAZIM; Şahin, AYNUR; Gündüz, ABDÜLKADİR; Yuluğ, ESİN; Türedi, SÜLEYMAN

doi:10.1016/j.ajem.2016.06.003

The effect of ethyl pyruvate and N-acetylcysteine on ischemia-reperfusion injury in an experimental model of ischemic stroke

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Turkmen S., Gonenc O. C., Karaca Y., Menteşe A., Demir S., Beyhun E., ...More

AMERICAN JOURNAL OF EMERGENCY MEDICINE, vol.34, no.9, pp.1804-1807, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 34 Issue: 9
Publication Date: 2016
Doi Number: 10.1016/j.ajem.2016.06.003
Journal Name: AMERICAN JOURNAL OF EMERGENCY MEDICINE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1804-1807
Karadeniz Technical University Affiliated: Yes

Abstract

Introduction: Reperfusion therapies play an important role in early-period treatment for patients presenting to the emergency department due to stroke. However, the ischemia-reperfusion injury that may occur with reperfusion must then be considered. The purpose of this study was to determine the effectiveness of N-acetylcysteine (NAC) and ethyl pyruvate in preventing ischemia-reperfusion injury.