Flow cytometric examination of apoptotic effect on brain tissue in postnatal period created by intrauterine oxcarbazepine and gabapentin exposure

Erisgin, Z.; Tekelioglu, YAVUZ

doi:10.4149/bll_2017_022

Flow cytometric examination of apoptotic effect on brain tissue in postnatal period created by intrauterine oxcarbazepine and gabapentin exposure

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Erisgin Z., Tekelioglu Y.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.118, no.2, pp.107-111, 2017 (SCI-Expanded)

Publication Type: Article / Article
Volume: 118 Issue: 2
Publication Date: 2017
Doi Number: 10.4149/bll_2017_022
Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.107-111
Karadeniz Technical University Affiliated: Yes

Abstract

OBJECTIVE: For epileptics, pregnancy contains the balance between no seizure period and antiepileptic use having the least teratogenicity risk. The purpose is to analyse with flow cytometry the apoptotic effects on postnatal brain tissue caused by prenatal use of second generation antiepileptics oxcarbazepine (OXC) and gabapentin (GBP) having different effect mechanisms.