<i>Papiliotrema</i><i> (Cryptococcus)</i><i> laurentii</i> Fungemia in an Infant with Prader Willi Syndrome

GAYRETLİ AYDIN Z. G., ÖZKAYA E., TOSUN İ.

JOURNAL OF PEDIATRIC INFECTION, sa.1, ss.57-60, 2023 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2023
  • Doi Numarası: 10.5578/ced.20239925
  • Dergi Adı: JOURNAL OF PEDIATRIC INFECTION
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, CAB Abstracts, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.57-60
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Papiliotrema laurentii, previously known as Cryptococcus laurentii, has rarely been diagnosed as the etiological pathogen able to cause human infections. Clinical manifestations of P. laurentii ranges from skin lesions to fungemia. P. laurentii fungemia has been reported extremely rare, espe-cially in patients with risk factors such as chemotherapy, corticosteroids, HIV infection, indwelling central venous catheter and prematurity. This study aimed to report a case of fungemia due to P. laurentii in an infant with Prader Willi Syndrome. Despite fluconazole treatment, yeast was iso-lated three times from blood cultures taken one day apart. Fluconazole was switched to liposomal amphotericin B (5 mg/kg) therapy and contin-ued for two weeks after the first report of unyielded Papiliotrema laurentii. The patient's clinical condition improved and was discharged home with-out any complication. To the best of our knowledge, this is the first case of P. laurentiifungemia in an immunocompetent infant.