Hitit medical journal (Online), cilt.8, sa.1, ss.48-55, 2026 (TRDizin)
Objective: Emergence agitation is a condition occurring in the early recovery phase of general anesthesia, negatively impacting patient comfort. It is particularly relevant in vitreoretinal surgery due to prolonged duration and changes in intraocular pressure. This study retrospectively compares the effects of different inhalation anesthetics on emergence agitation in such cases.Material and Method: A total of 254 ASA I–III patients who underwent vitreoretinal surgery were included. Based on anesthesia maintenance, patients were divided into two groups: sevoflurane (Group S) and desflurane (Group D). Hemodynamic data, extubation quality score, Richmond Agitation-Sedation Scale (RASS) scores at 0, 15, and 30 minutes, nausea-vomiting, and additional analgesic needs were evaluated from anesthesia records.Results: No significant differences were found between groups regarding demographics, surgery/anesthesia durations, extubation times, RASS scores, or extubation quality. However, Group D showed significantly higher heart rate at 30 and 60 minutes, and mean arterial pressure at 45 minutes.Conclusion: The choice of inhalation agent does not significantly impact emergence agitation in vitreoretinal surgery. However, desflurane may lead to increased intraoperative hemodynamic responses compared to sevoflurane.