Vitamin D and Hyperbilirubinaemia in Neonates

Mutlu M. , Cayir A., ÇAYIR Y., Ozkan B., ASLAN Y.

HONG KONG JOURNAL OF PAEDIATRICS, cilt.18, ss.77-81, 2013 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 18 Konu: 2
  • Basım Tarihi: 2013
  • Sayfa Sayıları: ss.77-81


Objectives: Low antioxidant system may contribute to the severity of neonatal hyperbilirubinaemia. This study Was performed with the aim of establishing whether there is a relationship between serum vitamin D level and the hyperbilirubinaemia in full-term neonates. Material and methods: This prospective study was performed by comparing serum vitamin D levels in newborns with a pathological level of hyperbilirubinaemia and healthy newborns with a physiological level of hyperbilirubinaemia or without jaundice. Ethical committee approval was obtained and written informed consent forms were received from babies families. Results: A statistically significant difference was found in the serum 25-hydroxy vitamin D levels between newborns with hyperbilirubinaemia and control group (p=0.01). A significant negative correlation was noted between serum vitamin D and serum parathyroid hormone levels among the neonates recruited (r:-0.3, p:0.03). Conclusions: Our results suggest that low level of serum vitamin D may associate with hyperbilirubinaemia in full-term neonates.