Neuroimmunophilin ligands protect cavernous nerves after crush injury in the rat: New experimental paradigms

VALENTINE H. , CHEN Y., GUO H., MCCORMICK J., WU Y., Sezen S. F. , ...More

EUROPEAN UROLOGY, vol.51, no.6, pp.1724-1731, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 6
  • Publication Date: 2007
  • Doi Number: 10.1016/j.eururo.2006.11.026
  • Title of Journal : EUROPEAN UROLOGY
  • Page Numbers: pp.1724-1731


Objectives: We investigated the effects of the orally bioavailable nonimmunosuppressive immunophilin ligand GPI 1046 (GPI) on erectile function and cavernous nerve (CN) histology following unilateral or bilateral crush injury (UCI, BCI, respectively) of the CNs.