Neuroimmunophilin ligands protect cavernous nerves after crush injury in the rat: New experimental paradigms

VALENTINE H., CHEN Y., GUO H., MCCORMICK J., WU Y., Sezen S. F., ...Daha Fazla

EUROPEAN UROLOGY, cilt.51, sa.6, ss.1724-1731, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 6
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.eururo.2006.11.026
  • Dergi Adı: EUROPEAN UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1724-1731
  • Anahtar Kelimeler: cavernous nerve injury, erectile dysfunction, immunophilin ligands, ENDOTHELIAL GROWTH-FACTOR, IMMUNOPHILIN-LIGANDS, RADICAL PROSTATECTOMY, ERECTILE DYSFUNCTION, NEUROTROPHIC FACTOR, IN-VIVO, REGENERATION, MODEL, RECOVERY, FK506
  • Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

Objectives: We investigated the effects of the orally bioavailable nonimmunosuppressive immunophilin ligand GPI 1046 (GPI) on erectile function and cavernous nerve (CN) histology following unilateral or bilateral crush injury (UCI, BCI, respectively) of the CNs.