Occupational exposure of dental technicians to methyl methacrylate: Genotoxicity assessment


Soykut B., Erdem O., YALÇIN C. Ö. , ÜSTÜNDAĞ A., DUYDU Y., Akay C., ...More

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, vol.852, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 852
  • Publication Date: 2020
  • Doi Number: 10.1016/j.mrgentox.2020.503159
  • Title of Journal : MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Abstract

Dental technicians may be chronically exposed to methyl methacrylate (MMA), used in the production of dental prostheses. We have studied whether occupational exposure to MMA affects genotoxicity biomarkers such as 8-OHdG formation, comet assay, and buccal micronucleus frequency. MMA exposure was assessed via ambient air analysis. Although no significant differences between exposed and non-exposed individuals were seen with respect to blood genotoxicity measurements, we found a higher level of buccal-cell anomalies in the exposed group.