GEBURTSHILFE UND FRAUENHEILKUNDE, cilt.65, sa.2, ss.195-198, 2005 (SCI-Expanded)
We report on a 30-year-old woman presenting with a four week history of continuous vaginal bleeding. Histopathological examination revealed a poorly differentiated botryoid type of embryonal rhabdomyosarcoma. The lesion was classified as group III according to the criteria of the Intergroup Rhabdomyosarcoma Study (IRS) Clinical Grouping Classification. After partial local tumor excision, the patient received radiation with chemotherapy according to a protocol consisting of 6 cycles with vincristine, adriamycin and cyclophosphamide (VAC). Although primary treatment remains surgery followed by adjuvant chemotherapy or radiation, the appropriate therapy for each stage of an embryonal rhabdomyosarcoma should be redefined and new studies are needed which would focus on the clinical course and take prognostic factors into consideration.