This study was performed to evaluate effects of driving torques on direct screw withdrawal resistance (DSWR) in OSB. Pilot hole diameters (1.6, 2, 2.4 mm), embedded screw orientations (edge-, end- and face-) and torque levels, that were obtained from the two main driving torques of seating and stripping, were selected to test on DSWR. The results of the study showed that the pilot hole diameters were needed to be chosen carefully related to the grain orientation and torque level. The DSWR in face orientation was higher than the ones in edge and end orientations. Based on the torque levels selected, the DSWR was lower at the torque level closer to the stripping torque levels in OSB.