Effects of Cilostazol on Oxidative Stress, Systemic Cytokine Release, and Spinal Cord Injury in a Rat Model of Transient Aortic Occlusion


Kurtoglu T., Basoglu H., Ozkisacik E. A., Cetin N. K., Tataroglu C., Yenisey C., ...Daha Fazla

ANNALS OF VASCULAR SURGERY, cilt.28, sa.2, ss.479-488, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.avsg.2013.08.005
  • Dergi Adı: ANNALS OF VASCULAR SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.479-488
  • Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

Background: Cilostazol is a phosphodiesterase inhibitor that has anti-inflammatory potential in addition to vasodilator and antiplatelet effects. The aim of this study was to determine the influence of cilostazol on biochemical markers of oxidative damage, proinflammatory cytokine release, and spinal cord injury after transient aortic occlusion in rats.