FK506-binding protein localizations in human penile innervation

Lagoda G., Sezen S. F., Liu T., Hoeke A., Burnett A. L.

BJU INTERNATIONAL, cilt.101, sa.5, ss.604-609, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 101 Sayı: 5
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1111/j.1464-410x.2007.07290.x
  • Dergi Adı: BJU INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.604-609
  • Anahtar Kelimeler: prostate, penis, FKBP, immunophilin, neurotrophic, nerve, CAVERNOUS NERVE INJURY, DEVELOPMENTAL REGULATION, RADICAL PROSTATECTOMY, CRUSH INJURY, IMMUNOPHILIN, LIGANDS, SYSTEM, FKBP65, FK506, RAT
  • Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

To determine if FK506-binding proteins (FKBPs) are localized to the autonomic nerve supply of the human penis because FK506 (an immunosuppressant drug) has been linked to enhanced nerve regeneration after nerve injury and neurodegenerative diseases by binding to FKBPs, a select group of immunophilins.