Studies on synthesis, structure, and DNA cleaving of homo-dinuclear Mn(II), Cu(II), Ni(II), and Zn(II) complexes with a heterocycle-based macroacyclic Schiff base


Baran T., Karaoglu K., Serbest K., Agir H., Sandalli C., DEĞİRMENCİOĞLU İ.

MONATSHEFTE FUR CHEMIE, cilt.144, ss.1107-1115, 2013 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 144 Konu: 8
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s00706-013-0926-6
  • Dergi Adı: MONATSHEFTE FUR CHEMIE
  • Sayfa Sayıları: ss.1107-1115

Özet

(E,E',E'',E''')-N,N',N'',N'''-[(1,2-ethenyliden)tetrakis[methylenoxy(2,1-naphthalinediyl)methylidyne]tetrakis[1,2,4-triazol-4-amine] and its novel homo-dinuclear Mn(II), Ni(II), Cu(II), and Zn(II) complexes have been synthesized and characterized by elemental analyses, spectroscopic data (i.e., IR, H-1 and C-13 NMR, UV-Vis), electrospray ionisation mass spectra, XRD, DSC, molar conductivity, and magnetic susceptibility measurements. The absorption bands observed in the electronic spectra and magnetic moment values confirm an octahedral environment around the metal ion. The molar conductivity measurements confirm the non-ionic character of these complexes. The DNA cleavage activities of the Schiff base and its homo-dinuclear complexes are also investigated. Results suggest that all the complexes used can be evaluated as nuclease mimics.