Liver involvement in children with Familial Mediterranean fever

Unal F., ÇAKIR M., Baran M., Arikan C., Yuksekkaya H. A., AYDOĞDU S.

DIGESTIVE AND LIVER DISEASE, cilt.44, sa.8, ss.689-693, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 8
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.dld.2012.01.003
  • Dergi Adı: DIGESTIVE AND LIVER DISEASE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.689-693
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Aim: Familial Mediterranean fever is characterised by recurrent, febrile, inflammatory attacks of the serosal membranes. Prolonged inflammatory response is triggered secondary to cytokine stimulation due to reduced activity of pyrin. Inflammatory cytokines play major role in the pathogenesis of acute liver injury; and chronic, recurrent cytokine production may cause chronic hepatitis/cirrhosis. We aimed to analyse liver involvement in children with Familial Mediterranean fever.