Akademik Veri Yönetim Sistemi
POLYHEDRON, cilt.207, 2021 (SCI-Expanded)
The novel metal-free (4) zinc(II) (5) and lead(II) (6) phthalocyanines containing 1,2,4-triazole groups connected to the phthalocyanine ring by S-bridge were synthesized and characterized. For this purpose, the original 2-(4-chlorobenzoy1)-N-(4-fluomphenyehydrazinecarbothioamide (1) was synthesized as a result of the reaction of 4chlorobenzyl hydrazide and 4-fluomphenyl isothiocyanate. It was obtained 5-(4-chlomphenyl)-4-(4 fluo ropheny1)-4H-1,2,4-triazole-3-thiol (2), which is a new compound by the ring closure reaction of 1. The other original compound 4-[5-(4 chlorophenyl)-4-(4 fluoropheny1)-4H-[1,2,4]triazol-3-yl sulfanyl]-phthalonitrile (3) was synthesized by the nucleophilic aromatic substitution reaction of 4-nitrophthalonitrile and compound 2. Starting from the new phthalonitrile (3), the metal-free (4), zinc(II) (5) and lead(II) (6) phthalocyanines (Pcs) were prepared. Six new compounds were synthesized, and their structures were characterized by elemental analysis and H-1 NMR, C-13 NMR, FT-IR, MALDI-TOF MS and UV-vis spectral data in this work. The photophysical and photochemical properties of the synthesized phthalocyanines were investigated for determination of their usability as photosensitizers (PS) for photodynamic therapy (PDT) applications. (C) 2021 Elsevier Ltd. All rights reserved.