Selective cytotoxic effect of Rhododendron luteum extract on human colon and liver cancer cells

DEMİR S., TURAN İ., ALİYAZICIOĞLU Y.

JOURNAL OF BUON, cilt.21, sa.4, ss.883-888, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 4
  • Basım Tarihi: 2016
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.883-888
  • Anahtar Kelimeler: antioxidant activity, cancer cell lines, cytotoxic effect, polyphenols, Rhododendron luteum, LUNG-CARCINOMA CELLS, NATURAL-PRODUCTS, ANTIOXIDANT PROPERTIES, CHEMICAL-CONSTITUENTS, ANTICANCER PROPERTIES, GENUS RHODODENDRON, MAD HONEY, FLAVONOIDS, PREVENTION, ERICACEAE
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Purpose: The genus Rhododendron is distributed entirely in the world with the exception of South and Central America and Africa, growing in a large diversity of climatic conditions. This genus is a rich source of phenolic compounds, especially flavonoids, essential oils, chromones, terpenoids, and steroids. It has many biological properties such as antioxidant, anti-inflammatory, antiviral, antibacterial, anticancer, antidiabetic, immunomodulatory, cardioprotective and hepatoprotective among others due to their polyphenolic constituents. The objective of the current study was to evaluate the antioxidant properties and cytotoxic activity of dimethyl sulfoxide extract of flowers of Rhododendron luteum (DEFR) for the first time.