Selective cytotoxic effect of Rhododendron luteum extract on human colon and liver cancer cells


DEMİR S. , TURAN İ., ALİYAZICIOĞLU Y.

JOURNAL OF BUON, cilt.21, ss.883-888, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 21 Konu: 4
  • Basım Tarihi: 2016
  • Dergi Adı: JOURNAL OF BUON
  • Sayfa Sayıları: ss.883-888

Özet

Purpose: The genus Rhododendron is distributed entirely in the world with the exception of South and Central America and Africa, growing in a large diversity of climatic conditions. This genus is a rich source of phenolic compounds, especially flavonoids, essential oils, chromones, terpenoids, and steroids. It has many biological properties such as antioxidant, anti-inflammatory, antiviral, antibacterial, anticancer, antidiabetic, immunomodulatory, cardioprotective and hepatoprotective among others due to their polyphenolic constituents. The objective of the current study was to evaluate the antioxidant properties and cytotoxic activity of dimethyl sulfoxide extract of flowers of Rhododendron luteum (DEFR) for the first time.