Effects of Interactions among Gene Polymorphisms of the Renin-Angiotensin-Aldosterone System on Hypertension in Turkish People from Southeast Anatolia

ARPACI, ABDULLAH; URHAN KÜÇÜK, MERAL; Bayramoglu, Aysegul; GÜLER, HALİL; Ecevit, Hasret; Suner, Arif; KARAKAŞ ÇELİK, SEVİM

doi:10.2478/rrlm-2019-0011

Effects of Interactions among Gene Polymorphisms of the Renin-Angiotensin-Aldosterone System on Hypertension in Turkish People from Southeast Anatolia

ARPACI A., URHAN KÜÇÜK M., Bayramoglu A., GÜLER H. İ., Ecevit H., Suner A., ...Daha Fazla

REVISTA ROMANA DE MEDICINA DE LABORATOR, cilt.27, sa.2, ss.159-168, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 27 Sayı: 2
Basım Tarihi: 2019
Doi Numarası: 10.2478/rrlm-2019-0011
Dergi Adı: REVISTA ROMANA DE MEDICINA DE LABORATOR
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
Sayfa Sayıları: ss.159-168
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Introduction: Hypertension (HT) is characterized by high blood pressure. The reninangiotensin-aldosterone system (RAAS) plays a crucial role in blood pressure (BP) regulation by maintaining vascular tone and the water-sodium balance. We aimed to investigate whether there is any relation between AGT (M235T), ACE (I/D), and AGTR1 (A1166C) genetic polymorphisms and hypertension among Turkish people from Southeast Anatolia.