Effects of Interactions among Gene Polymorphisms of the Renin-Angiotensin-Aldosterone System on Hypertension in Turkish People from Southeast Anatolia

ARPACI, ABDULLAH; URHAN KÜÇÜK, MERAL; Bayramoglu, Aysegul; GÜLER, HALİL; Ecevit, Hasret; Suner, Arif; KARAKAŞ ÇELİK, SEVİM

doi:10.2478/rrlm-2019-0011

Effects of Interactions among Gene Polymorphisms of the Renin-Angiotensin-Aldosterone System on Hypertension in Turkish People from Southeast Anatolia

ARPACI A., URHAN KÜÇÜK M., Bayramoglu A., GÜLER H. İ., Ecevit H., Suner A., ...More

REVISTA ROMANA DE MEDICINA DE LABORATOR, vol.27, no.2, pp.159-168, 2019 (SCI-Expanded)

Publication Type: Article / Article
Volume: 27 Issue: 2
Publication Date: 2019
Doi Number: 10.2478/rrlm-2019-0011
Journal Name: REVISTA ROMANA DE MEDICINA DE LABORATOR
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
Page Numbers: pp.159-168
Open Archive Collection: AVESIS Open Access Collection
Karadeniz Technical University Affiliated: Yes

Abstract

Introduction: Hypertension (HT) is characterized by high blood pressure. The reninangiotensin-aldosterone system (RAAS) plays a crucial role in blood pressure (BP) regulation by maintaining vascular tone and the water-sodium balance. We aimed to investigate whether there is any relation between AGT (M235T), ACE (I/D), and AGTR1 (A1166C) genetic polymorphisms and hypertension among Turkish people from Southeast Anatolia.