Drug-induced Acute Lung Injury: A Comprehensive Radiologic Review

Hamishegi F. S., Singh R., Baruah D., Chamberlin J., Hamouda M., AKKAYA S., ...Daha Fazla

Journal of Thoracic Imaging, 2024 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1097/rti.0000000000000816
  • Dergi Adı: Journal of Thoracic Imaging
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, MEDLINE
  • Anahtar Kelimeler: acute lung injury, chest, computed Tomography, drug toxicity, pneumonitis
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Drug-induced acute lung injury is a significant yet often underrecognized clinical challenge, associated with a wide range of therapeutic agents, including chemotherapy drugs, antibiotics, anti-inflammatory drugs, and immunotherapies. This comprehensive review examines the pathophysiology, clinical manifestations, and radiologic findings of drug-induced acute lung injury across different drug categories. Common imaging findings are highlighted to aid radiologists and clinicians in early recognition and diagnosis. The review emphasizes the importance of immediate cessation of the offending drug and supportive care, which may include corticosteroids. Understanding these patterns is crucial for prompt diagnosis and management, potentially improving patient outcomes.