Synthesis and bio-molecular study of (+)-N-Acetyl-a-amino acid dehydroabietylamine derivative for the selective therapy of hepatocellular carcinoma

MUSTUFA M. A. , Ozen C., HASHMI I. A. , ASLAM A., BAIG J. A. , Yildiz G., ...More

BMC CANCER, vol.16, 2016 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16
  • Publication Date: 2016
  • Doi Number: 10.1186/s12885-016-2942-5
  • Journal Name: BMC CANCER
  • Journal Indexes: Science Citation Index Expanded, Scopus


Background: The purpose of present work is to synthesize novel (+)-Dehydroabietylamine derivatives (DAAD) using N-acetyl-a-amino acid conjugates and determine its cytotoxic effects on hepatocellular carcinoma cells.