Synthesis and bio-molecular study of (+)-N-Acetyl-a-amino acid dehydroabietylamine derivative for the selective therapy of hepatocellular carcinoma

MUSTUFA M. A., Ozen C., HASHMI I. A., ASLAM A., BAIG J. A., Yildiz G., ...More

BMC CANCER, vol.16, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16
  • Publication Date: 2016
  • Doi Number: 10.1186/s12885-016-2942-5
  • Journal Name: BMC CANCER
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Karadeniz Technical University Affiliated: No


Background: The purpose of present work is to synthesize novel (+)-Dehydroabietylamine derivatives (DAAD) using N-acetyl-a-amino acid conjugates and determine its cytotoxic effects on hepatocellular carcinoma cells.