Presence and characterization of prostaglandin D2-related molecules in nasal mucosa of patients with allergic rhinitis


OKANO M., FUJIWARA T., SUGATA Y., GOTOH D., MASAOKA Y., SOGO M., ...Daha Fazla

AMERICAN JOURNAL OF RHINOLOGY, cilt.20, sa.3, ss.342-348, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Konu: 3
  • Basım Tarihi: 2006
  • Doi Numarası: 10.2500/ajr.2006.20.2865
  • Dergi Adı: AMERICAN JOURNAL OF RHINOLOGY
  • Sayfa Sayıları: ss.342-348

Özet

Background: Prostaglandin D2 (PGD2) is the major prostanoid produced in the acute phase of allergic reactions. However, its pathophysiological role in addition to the pathway of production in allergic rhinitis remains unclear. We sought to determine the expression of synthases and receptors for PGD2 in human nasal mucosa. These expressions were compared between allergic and nonallergic patients.