Presence and characterization of prostaglandin D2-related molecules in nasal mucosa of patients with allergic rhinitis

OKANO, Mitsuhiro; FUJIWARA, Tazuko; SUGATA, Yuji; GOTOH, Daisuke; MASAOKA, Yoshihisa; SOGO, Masahiro; TANIMOTO, Wakana; YAMAMOTO, Miki; MATSUMOTO, Rie; EGUCHI, Naomi; KINIWA, Mamoru; Isik, ABDÜLCEMAL; URADE, Yoshihiro; NISHIZAKI, Kazunori

doi:10.2500/ajr.2006.20.2865

Presence and characterization of prostaglandin D2-related molecules in nasal mucosa of patients with allergic rhinitis

Atıf İçin Kopyala

OKANO M., FUJIWARA T., SUGATA Y., GOTOH D., MASAOKA Y., SOGO M., ...Daha Fazla

AMERICAN JOURNAL OF RHINOLOGY, cilt.20, sa.3, ss.342-348, 2006 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 20 Sayı: 3
Basım Tarihi: 2006
Doi Numarası: 10.2500/ajr.2006.20.2865
Dergi Adı: AMERICAN JOURNAL OF RHINOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.342-348
Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background: Prostaglandin D2 (PGD2) is the major prostanoid produced in the acute phase of allergic reactions. However, its pathophysiological role in addition to the pathway of production in allergic rhinitis remains unclear. We sought to determine the expression of synthases and receptors for PGD2 in human nasal mucosa. These expressions were compared between allergic and nonallergic patients.