In vitro effects of sodium nitroprusside and leptin on norepinephrine-induced vasoconstriction in human internal mammary artery

Burma, Oktay; ÖZCAN, METE; KAÇAR, EMİNE; Uysal, Ayhan; ŞAHNA, ENGİN; AYAR, AHMET

doi:10.5830/cvja-2014-041

In vitro effects of sodium nitroprusside and leptin on norepinephrine-induced vasoconstriction in human internal mammary artery

Burma O., ÖZCAN M., KAÇAR E., Uysal A., ŞAHNA E., AYAR A.

CARDIOVASCULAR JOURNAL OF AFRICA, cilt.26, sa.1, ss.4-7, 2015 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 26 Sayı: 1
Basım Tarihi: 2015
Doi Numarası: 10.5830/cvja-2014-041
Dergi Adı: CARDIOVASCULAR JOURNAL OF AFRICA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.4-7
Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Aim: The biological and pharmacological properties of vessels used in coronary artery bypass graft (CABG) surgery are as important as their mechanical properties. The aim of this study was to investigate the possible role of protein kinase C (PKC)-dependent mechanisms in leptin-induced relaxation in the human internal mammary artery (IMA).