In vitro effects of sodium nitroprusside and leptin on norepinephrine-induced vasoconstriction in human internal mammary artery


Burma O., ÖZCAN M., KAÇAR E., Uysal A., ŞAHNA E., AYAR A.

CARDIOVASCULAR JOURNAL OF AFRICA, vol.26, no.1, pp.4-7, 2015 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 26 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.5830/cvja-2014-041
  • Journal Name: CARDIOVASCULAR JOURNAL OF AFRICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.4-7
  • Karadeniz Technical University Affiliated: Yes

Abstract

Aim: The biological and pharmacological properties of vessels used in coronary artery bypass graft (CABG) surgery are as important as their mechanical properties. The aim of this study was to investigate the possible role of protein kinase C (PKC)-dependent mechanisms in leptin-induced relaxation in the human internal mammary artery (IMA).